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Automating Protein Purification

Protein purification can be complex and time-consuming. Automating your protein purification workflow can increase efficiency, reduce errors and save hands-on time. Protein purification methods that are most adaptable to automation use magnetic beads or dual flow chromatography columns.

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Automating magnetic bead-based protein purification

Learn how to automate magnetic bead-based protein purification with the OT-2 using Thermo Fisher Dynabeads™ Protein A/Protein G & Thermo Fisher Pierce™ Ni-NTA Magnetic Agarose Beads.

Magnetic Bead Protein Purification Workstation

Automate protein purification on the Opentrons Flex

FLEX PP Workstation 1ch 8ch 2024

With the Flex Magnetic Bead Protein Purification Workstation, you can automate your bead-based protein purification workflow at the scale you need to increase efficiency, reduce errors, and save hands-on time. Flex enables you to automate small-scale isolation of specific proteins, protein complexes, and antibodies, or proteomics sample processing, using many leading magnetic bead-based reagent systems on the market.

Webinar & Application Note

Immunoprecipitation using Thermo Fisher Dynabeads on the OT-2

Webinar & Application Note

Ni-NTA bead-based protein purification on the OT-2

OT-2 Dual Flow Chromatography Protein Purification Workstation

Use the OT-2 to automate small-scale, dual flow chromatography protein purification using Biotage® PhyTip® columns.


Protein purification with Biotage PhyTip Columns on the OT-2

Perform dual flow chromatography using Biotage® PhyTip® columns on the Opentrons OT-2 liquid handler.


*Verification categories:
Opentrons = has been verified by the Opentrons Team, who verify that the scientific results are as expected.
Partner = has been verified by our reagent partner, who verifies that the scientific results are as expected.
Community = protocol is in use by members of the Opentrons community.


Want to know more?

Our team of experts can help figure out if automation is right for you. Book a virtual demo to discuss your workflow needs with an expert.