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Publications

Synthetic Genetic Codes Designed to Hinder Evolution

One challenge in engineering organisms is guaranteeing system behavior over many generations. Spontaneous mutations that arise before or during use…

Publications

Drag-and-drop Genome Insertion without DNA Cleavage with CRISPR-Directed Integrases

Programmable and multiplexed genome integration of large, diverse DNA cargo independent of DNA repair remains an unsolved challenge of genome…

Publications

Rapid Production and Recovery of Cell Spheroids by Automated Droplet Microfluidics

The future of the life sciences is linked to automation and microfluidics. As robots start working side by side with…

Publications

Improving Reproducibility in Synthetic Biology

Synthetic biology holds great promise to deliver transformative technologies to the world in the coming years. However, several challenges still…

Publications

DNA-BOT: A Low-Cost, Automated DNA Assembly Platform For Synthetic Biology

Multi-part DNA assembly is the physical starting point for many projects in Synthetic and Molecular Biology. The ability to explore…

Publications

Unlocking The Efficiency of Genomics Laboratories With Robotic Liquid-Handling

In research and clinical genomics laboratories today, sample preparation is the bottleneck of experiments, particularly when it comes to high-throughput…

Publications

OpenWorkstation: A Modular Open-Source Technology For Automated In Vitro Workflows

Automation liberates scientific staff from repetitive tasks, decreases the probability of human error and consequently enhances the reproducibility of lab…

Publications

An Open Source Technology Platform to Manufacture Hydrogel-Based 3D Culture Models in an Automated and Standardized Fashion

This protocol serves as a comprehensive tutorial for standardized and reproducible mixing of viscous materials with a novel open source…

Publications

An Open-Source Technology Platform To Increase Reproducibility And Enable High-Throughput Production Of Tailorable Gelatin Methacryloyl (GelMA) – Based Hydrogels

Gelatin methacryloyl (GelMA)-based hydrogels have become highly studied as modular tissue culture platforms due to the combination of the …

Publications

Automation in the Life Science Research Laboratory

Protocols in the academic life science laboratory are heavily reliant on the manual manipulation of tools, reagents and instruments by…

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