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Leveraging open hardware to alleviate the burden of COVID-19 on global health systems

With the current rapid spread of COVID-19, global health systems are increasingly overburdened by the sheer number of people that need diagnosis, isolation and treatment. Shortcomings are evident across the board, from staffing, facilities for rapid and reliable testing to availability of hospital beds and key medical-grade equipment. Read More

An Open-Source Framework for Automated High-Throughput Cell Biology Experiments

Modern data analysis methods, such as optimization algorithms or deep learning have been successfully applied to a number of biotechnological and medical questions. For these methods to be efficient, a large number of high-quality and reproducible experiments needs to be conducted, requiring a high degree of automation. … Read More

Automation of an assay to determine hydrogen peroxide levels in THP-1 cells on the OT-2 Poster

Hydrogen peroxide (H2O2) is predominantly associated with cellular damage; however, recent studies show that cells release low levels of H2O2 as part of normal intercellular communication. The mechanisms of hydrogen peroxide transport, uptake and release, and biological effects are not yet well known but have important implications for cancer, stem… Read More

Opentrons COVID-19 Testing System One Sheeter

The Opentrons COVID-19 Testing System is a flexible, high-throughput surveillance testing system using OT-2 hardware & validated withZymo reagents to process up to 2,400 samples per day. Read More

Automating DNA Library Preparation of Small Genomes using Illumina ® DNA Preparation Kit on the Opentrons OT-2

The next-generation sequencing (NGS) workflow includes preparing DNA libraries using commercially available and cost-effective DNA preparation kits. Optimizing this workflow by using an automated OT-2 protocol helps to improve the efficiency for DNA library preparation. Read More

Automating NGS Library Prep eBook

Valuable NGS data depends on quality library preparation; insightful sequencing relies on unbiased library coverage with good yields. Read More

Automating PCR eBook

PCR is a molecular biology workhorse that is used for detecting and quantifying specific genes and is an important component of downstream applications including genomics and transcriptomics. Read More

Rapid High Quality Next Generation Sequencing Library Preparation With Swift 2S Turbo DNA Library Kits© On The Opentrons OT-2

The Swift 2Sâ„¢ Turbo DNA Library Kit was automated with the Opentrons OT-2 for fast and robust preparation of high quality libraries for next generation sequencing. Read More

Affordable COVID-19 Testing Automation With The Opentrons OT-2

Using the Opentron’s OT-2 and platform, we demonstrate a highly sensitive, affordable, and hands-off pipeline for PCR-based SARS-CoV-2 testing. Read More

Automated, Rapid & Reproducible Measurement Of Immunoglobulin G Using Opentrons OT-2, Valita®TITER and Valita®TITER Plus

Biologic drugs are the largest and fastest growing segment of the Pharmaceutical industry, with sales of €500bn and an annual growth of 8%.1 Their ability to target diseases with high specificity results in improved safety and effectiveness. However, this increases the cost of manufacturing significantly over their predecessors. Read More