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Partner Spotlight: Neochromosome

Genome-scale biological engineering

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Neochromosome is a pioneering synthetic biology company, dedicated to unlocking the full potential of genome-scale cell engineering. As a subsidiary of Opentrons, Neochromosome brings advanced tools and platforms to labs working at the frontier of biologics, therapeutics, and genetic innovation.

Introducing neoSwitchTM

neoSwitch is Neochromosome’s turnkey, yeast-based platform for in-house antibody discovery. Designed to seamlessly switch between yeast surface display and protein secretion, neoSwitch eliminates time-consuming steps like subcloning and protein expression. With access to Neochromosome’s ready-made or custom high-diversity libraries, labs can launch discovery campaigns with minimal setup and maximum efficiency.

Automated Antibody Discovery with the Opentrons Flex neoSwitch Workstation

The Opentrons Flex neoSwitch Workstation automates key steps of the neoSwitch workflow—including high-throughput purification of secreted binders, protein quantification, genotype identification in each clone via colony PCR and library preparation for sequencing. With pre-loaded, walkaway protocols and seamless integration of Flex’s automation capabilities, labs can scale antibody discovery internally, with full control over their R&D pipelines.

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Product Sheet

Discover neoSwitch, part of Neo’s Antibody Discovery Toolkit

Review neoSwitch validation data

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Webinar

How neoSwitch & Opentrons Flex Unlock Scalable Automation

Watch live on June 4, 2025 at 1:00 PM ET.

Demo

Flex Fits You

Find out more about Opentrons Flex from an automation expert