Neochromosome is a pioneering synthetic biology company, dedicated to unlocking the full potential of genome-scale cell engineering. As a subsidiary of Opentrons, Neochromosome brings advanced tools and platforms to labs working at the frontier of biologics, therapeutics, and genetic innovation.
neoSwitch is Neochromosome’s turnkey, yeast-based platform for in-house antibody discovery. Designed to seamlessly switch between yeast surface display and protein secretion, neoSwitch eliminates time-consuming steps like subcloning and protein expression. With access to Neochromosome’s ready-made or custom high-diversity libraries, labs can launch discovery campaigns with minimal setup and maximum efficiency.
The Opentrons Flex neoSwitch Workstation automates key steps of the neoSwitch workflow—including high-throughput purification of secreted binders, protein quantification, genotype identification in each clone via colony PCR and library preparation for sequencing. With pre-loaded, walkaway protocols and seamless integration of Flex’s automation capabilities, labs can scale antibody discovery internally, with full control over their R&D pipelines.
Review neoSwitch validation data
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